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SP-A Permeabilizes Lipopolysaccharide Membranes by Forming Protein Aggregates that Extract Lipids from the Membrane

Surfactant protein A (SP-A) is known to cause bacterial permeabilization. The aim of this work was to gain insight into the mechanism by which SP-A induces permeabilization of rough lipopolysaccharide (Re-LPS) membranes. In the presence of calcium, large interconnected aggregates of fluorescently la...

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Detalhes bibliográficos
Main Authors: Cañadas, Olga, García-Verdugo, Ignacio, Keough, Kevin M. W., Casals, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547440/
https://ncbi.nlm.nih.gov/pubmed/18599636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.137323
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