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Potential for Modulation of the Hydrophobic Effect Inside Chaperonins

Despite the spontaneity of some in vitro protein-folding reactions, native folding in vivo often requires the participation of barrel-shaped multimeric complexes known as chaperonins. Although it has long been known that chaperonin substrates fold upon sequestration inside the chaperonin barrel, the...

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Bibliographic Details
Main Authors: England, Jeremy L., Pande, Vijay S.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547425/
https://ncbi.nlm.nih.gov/pubmed/18599630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.131037
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