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A Role for Confined Water in Chaperonin Function

[Image: see text] Chaperonins engulf other proteins and accelerate their folding by an unknown mechanism. Here, we combine all-atom molecular dynamics simulations with data from experimental assays of the activity of the bacterial chaperonin GroEL to demonstrate that a chaperonin’s ability to facili...

詳細記述

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書誌詳細
主要な著者: England, Jeremy L., Lucent, Del, Pande, Vijay S.
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2008
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646679/
https://ncbi.nlm.nih.gov/pubmed/18710231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja802248m
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