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A Role for Confined Water in Chaperonin Function
[Image: see text] Chaperonins engulf other proteins and accelerate their folding by an unknown mechanism. Here, we combine all-atom molecular dynamics simulations with data from experimental assays of the activity of the bacterial chaperonin GroEL to demonstrate that a chaperonin’s ability to facili...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Chemical Society
2008
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646679/ https://ncbi.nlm.nih.gov/pubmed/18710231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja802248m |
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