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The Total Synthesis of Neoamphimedine

[Image: see text] Neoamphimedine, a Pyridoacridine alkaloid from Xestospongia sp., is a potent antitumor agent both in vitro and in vivo. Neoamphimedine can efficiently induce topoisomerase II mediated catenation of plasmid DNA in vitro, and is the only member of more than one hundred pyridoacridine...

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Bibliografiske detaljer
Main Authors: LaBarbera, Daniel V., Bugni, Tim S., Ireland, Chris M.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547140/
https://ncbi.nlm.nih.gov/pubmed/17900144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo7017813
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