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In vitro phenotypic markers of a poliovirus recombinant constructed from infectious cDNA clones of the neurovirulent Mahoney strain and the attenuated Sabin 1 strain.

Infectious cDNA corresponding to the entire genome of the attenuated Sabin strain of type 1 poliovirus has been inserted into EcoRI site of bacterial plasmid pBR325. Two consecutive PstI fragments (nucleotide positions 1814 to 3421) of the infectious cDNA of the Sabin 1 strain were replaced by the c...

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Bibliographic Details
Main Authors: Kohara, M, Omata, T, Kameda, A, Semler, B L, Itoh, H, Wimmer, E, Nomoto, A
Format: Artigo
Language:Inglês
Published: 1985
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC254708/
https://ncbi.nlm.nih.gov/pubmed/2983090
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