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Identification and Characterization of Shiga Toxin Type 2 Variants in Escherichia coli Isolates from Animals, Food, and Humans

There is considerable heterogeneity among the Shiga toxin type 2 (Stx2) toxins elaborated by Shiga toxin-producing Escherichia coli (STEC). One such Stx2 variant, the Stx2d mucus-activatable toxin (Stx2dact), is rendered more toxic by the action of elastase present in intestinal mucus, which cleaves...

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Bibliographic Details
Main Authors: Zheng, Jie, Cui, Shenghui, Teel, Louise D., Zhao, Shaohua, Singh, Ruby, O'Brien, Alison D., Meng, Jianghong
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547040/
https://ncbi.nlm.nih.gov/pubmed/18658282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00503-08
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