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Deficiency of Mbd2 Attenuates Wnt Signaling

We have previously shown that deficiency of the methyl binding domain protein Mbd2 dramatically reduces adenoma burden on an Apc(Min/+) background. To investigate the mechanism underlying this phenomenon, we have determined the effect of Mbd2 deficiency upon the phenotypes imposed by the conditional...

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Hlavní autoři: Phesse, Toby J., Parry, Lee, Reed, Karen R., Ewan, Kenneth B., Dale, Trevor C., Sansom, Owen J., Clarke, Alan R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547016/
https://ncbi.nlm.nih.gov/pubmed/18644872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00539-08
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