Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo

Por Flanagan, Dustin J., Barker, Nick, Nowell, Cameron, Clevers, Hans, Ernst, Matthias, Phesse, Toby J., Vincan, Elizabeth
Publicado no Dis Model Mech (2017)

Deficiency of Mbd2 Attenuates Wnt Signaling

Por Phesse, Toby J., Parry, Lee, Reed, Karen R., Ewan, Kenneth B., Dale, Trevor C., Sansom, Owen J., Clarke, Alan R.
Publicado em 2008

Rapid Loss of Intestinal Crypts upon Conditional Deletion of the Wnt/Tcf-4 Target Gene c-Myc

Por Muncan, Vanesa, Sansom, Owen J., Tertoolen, Leon, Phesse, Toby J., Begthel, Harry, Sancho, Elena, Cole, Alicia M., Gregorieff, Alex, de Alboran, Ignacio Moreno, Clevers, Hans, Clarke, Alan R.
Publicado em 2006

The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis

Por Pearson, Helen B., McGlinn, Edwina, Phesse, Toby J., Schlüter, Holger, Srikumar, Anuratha, Gödde, Nathan J., Woelwer, Christina B., Ryan, Andrew, Phillips, Wayne A., Ernst, Matthias, Kaur, Pritinder, Humbert, Patrick
Publicado no Mol Cancer (2015)

Frizzled7 Functions as a Wnt Receptor in Intestinal Epithelial Lgr5(+) Stem Cells

Por Flanagan, Dustin J., Phesse, Toby J., Barker, Nick, Schwab, Renate H.M., Amin, Nancy, Malaterre, Jordane, Stange, Daniel E., Nowell, Cameron J., Currie, Scott A., Saw, Jarel T.S., Beuchert, Eva, Ramsay, Robert G., Sansom, Owen J., Ernst, Matthias, Clevers, Hans, Vincan, Elizabeth
Publicado no Stem Cell Reports (2015)

Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc Signaling

Por Ashton, Gabrielle H., Morton, Jennifer P., Myant, Kevin, Phesse, Toby J., Ridgway, Rachel A., Marsh, Victoria, Wilkins, Julie A., Athineos, Dimitris, Muncan, Vanesa, Kemp, Richard, Neufeld, Kristi, Clevers, Hans, Brunton, Valerie, Winton, Douglas J., Wang, Xiaoyan, Sears, Rosalie C., Clarke, Alan R., Frame, Margaret C., Sansom, Owen J.
Publicado em 2010