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A Mobile Functional Region of Kaposi's Sarcoma-Associated Herpesvirus ORF50 Protein Independently Regulates DNA Binding and Protein Abundance

The protein encoded by open reading frame 50 (ORF50) of Kaposi's sarcoma-associated herpesvirus (KSHV) functions as a transcriptional activator and in lytic viral DNA replication to mediate the switch from latent viral infection to the lytic phase. Here we identify regulatory regions of ORF50 p...

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Autores principales: Chang, Pey-Jium, Shedd, Duane, Miller, George
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546948/
https://ncbi.nlm.nih.gov/pubmed/18653447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00862-08
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