Human Immunodeficiency Virus Type 1 Vpr-Binding Protein VprBP, a WD40 Protein Associated with the DDB1-CUL4 E3 Ubiquitin Ligase, Is Essential for DNA Replication and Embryonic Development

Damaged DNA binding protein 1, DDB1, bridges an estimated 90 or more WD40 repeats (DDB1-binding WD40, or DWD proteins) to the CUL4-ROC1 catalytic core to constitute a potentially large number of E3 ligase complexes. Among these DWD proteins is the human immunodeficiency virus type 1 (HIV-1) Vpr-bind...

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Main Authors: McCall, Chad M., Miliani de Marval, Paula L., Chastain, Paul D., Jackson, Sarah C., He, Yizhou J., Kotake, Yojiro, Cook, Jeanette Gowen, Xiong, Yue
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546929/
https://ncbi.nlm.nih.gov/pubmed/18606781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00232-08
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