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Induction of the Gα(q) Signaling Cascade by the Human Immunodeficiency Virus Envelope Is Required for Virus Entry

Binding of human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) with the primary receptor CD4 and one of two coreceptors, CXCR4 or CCR5, activates a signaling cascade resulting in Rac-1 GTPase activation and stimulation of actin cytoskeletal reorganizations critical for HIV-1-medi...

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Detaylı Bibliyografya
Asıl Yazarlar: Harmon, Brooke, Ratner, Lee
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546909/
https://ncbi.nlm.nih.gov/pubmed/18632858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00424-08
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