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Induction of the Gα(q) Signaling Cascade by the Human Immunodeficiency Virus Envelope Is Required for Virus Entry
Binding of human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) with the primary receptor CD4 and one of two coreceptors, CXCR4 or CCR5, activates a signaling cascade resulting in Rac-1 GTPase activation and stimulation of actin cytoskeletal reorganizations critical for HIV-1-medi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2546909/ https://ncbi.nlm.nih.gov/pubmed/18632858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00424-08 |
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