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Tumor Necrosis Factor Alpha Protects against Lethal West Nile Virus Infection by Promoting Trafficking of Mononuclear Leukocytes into the Central Nervous System

West Nile virus (WNV) is a neurotropic flavivirus that has emerged globally as a significant cause of viral encephalitis in humans, especially in immunocompromised individuals. Previous studies have shown essential protective roles for antiviral cytokines (e.g., alpha interferon [IFN-α] and IFN-γ) a...

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Detalhes bibliográficos
Main Authors: Shrestha, Bimmi, Zhang, Bo, Purtha, Whitney E., Klein, Robyn S., Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546880/
https://ncbi.nlm.nih.gov/pubmed/18632856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01118-08
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