Identification of the Smallest Structure Capable of Evoking Opsonophagocytic Antibodies against Streptococcus pneumoniae Type 14

Synthetic overlapping oligosaccharide fragments of Streptococcus pneumoniae serotype 14 capsular polysaccharide (Pn14PS), {6)-[β-d-Galp-(1→4)-]β-d-GlcpNAc-(1→3)-β-d-Galp-(1→4)-β-d-Glcp-(1→}(n), were conjugated to CRM(197) protein and injected into mice to determine the smallest immunogenic structure...

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Bibliographic Details
Main Authors: Safari, Dodi, Dekker, Huberta A. T., Joosten, John A. F., Michalik, Dirk, de Souza, Adriana Carvalho, Adamo, Roberto, Lahmann, Martina, Sundgren, Andreas, Oscarson, Stefan, Kamerling, Johannis P., Snippe, Harm
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546832/
https://ncbi.nlm.nih.gov/pubmed/18678667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00472-08
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