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A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity

MicroRNAs (miRNAs) and transcription factors (TFs) are primary metazoan gene regulators. Whereas much attention has focused on finding the targets of both miRNAs and TFs, the transcriptional networks that regulate miRNA expression remain largely unexplored. Here, we present the first genome-scale Ca...

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Detalhes bibliográficos
Main Authors: Martinez, Natalia J., Ow, Maria C., Barrasa, M. Inmaculada, Hammell, Molly, Sequerra, Reynaldo, Doucette-Stamm, Lynn, Roth, Frederick P., Ambros, Victor R., Walhout, Albertha J.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546694/
https://ncbi.nlm.nih.gov/pubmed/18794350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1678608
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