Gender-Dependent HLA-DR-Restricted Epitopes Identified from Herpes Simplex Virus Type 1 Glycoprotein D

In recent clinical trials, a herpes simplex virus (HSV) recombinant glycoprotein D (gD) vaccine was more efficacious in woman than in men. Here we report six HLA-DR-restricted T-cell gD epitope peptides that bind to multiple HLA-DR (DR1, DR4, DR7, DR13, DR15, and DRB5) molecules that represent a lar...

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Hlavní autoři: Zhang, Xiuli, Castelli, Florence A., Zhu, Xiaoming, Wu, Michele, Maillère, Bernard, BenMohamed, Lbachir
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Vaccine Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546687/
https://ncbi.nlm.nih.gov/pubmed/18667634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00123-08
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