Distinct Contributions of the Nisin Biosynthesis Enzymes NisB and NisC and Transporter NisT to Prenisin Production by Lactococcus lactis

Several Lactococcus lactis strains produce the lantibiotic nisin. The dedicated enzymes NisB and NisC and the transporter NisT modify and secrete the ribosomally synthesized nisin precursor peptide. NisB can function in the absence of the cyclase NisC, yielding the dehydrated prenisin that lacks the...

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Hauptverfasser: van den Berg van Saparoea, H. Bart, Bakkes, Patrick J., Moll, Gert N., Driessen, Arnold J. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Enzymology and Protein Engineering
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546625/
https://ncbi.nlm.nih.gov/pubmed/18621866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00342-08
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