S100A1 and Calmodulin Compete for the Same Binding Site on Ryanodine Receptor

In heart and skeletal muscle an S100 protein family member, S100A1, binds to the ryanodine receptor (RyR) and promotes Ca(2+) release. Using competition binding assays, we further characterized this system in skeletal muscle and showed that Ca(2+)-S100A1 competes with Ca(2+)-calmodulin (CaM) for the...

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Библиографические подробности
Главные авторы: Wright, Nathan T., Prosser, Benjamin L., Varney, Kristen M., Zimmer, Danna B., Schneider, Martin F., Weber, David J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2008
Предметы:
Protein Structure and Folding
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546546/
https://ncbi.nlm.nih.gov/pubmed/18650434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804432200
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