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Mouse Maelstrom, a component of nuage, is essential for spermatogenesis and transposon repression in meiosis

Tight control of transposon activity is essential for the integrity of the germline. Recently, a germ cell-specific organelle, nuage, was proposed to play a role in transposon repression. To test this hypothesis, we disrupted a murine homolog of a Drosophila nuage protein Maelstrom. Effects on male...

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Bibliografiske detaljer
Main Authors: Soper, Sarah F.C., van der Heijden, Godfried W., Hardiman, Tara C., Goodheart, Mary, Martin, Sandra L., de Boer, Peter, Bortvin, Alex
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546488/
https://ncbi.nlm.nih.gov/pubmed/18694567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.05.015
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