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Mouse Maelstrom, a component of nuage, is essential for spermatogenesis and transposon repression in meiosis
Tight control of transposon activity is essential for the integrity of the germline. Recently, a germ cell-specific organelle, nuage, was proposed to play a role in transposon repression. To test this hypothesis, we disrupted a murine homolog of a Drosophila nuage protein Maelstrom. Effects on male...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2546488/ https://ncbi.nlm.nih.gov/pubmed/18694567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.05.015 |
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