Mutations in the hemagglutinin receptor-binding site can change the biological properties of an influenza virus.
Avian influenza virus reassortants containing human influenza virus hemagglutinins do not replicate in ducks. Two mutations in the receptor-binding site of a human hemagglutinin at residues 226 and 228 allowed replication in ducks. The mutations resulted in a receptor-binding-site sequence identical...
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| Опубликовано в:: | J Virol |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
1984
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254476/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6748165/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.51.2.567-569.1984 |
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