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Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Semisynthesis of Salvinicins A and B and Other Chemical Transformations of Salvinorin A

Salvinorin A (1) is a hallucinogenic neoclerodane diterpene isolated from the widely available psychoactive plant Salvia divinorum and is the first example of a non-nitrogenous opioid receptor ligand. At present, there is little information available as to why this compound is selective for κ opioid...

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Detalhes bibliográficos
Main Authors: Harding, Wayne W., Schmidt, Matthew, Tidgewell, Kevin, Kannan, Pavitra, Holden, Kenneth G., Gilmour, Brian, Navarro, Hernan, Rothman, Richard B., Prisinzano, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544632/
https://ncbi.nlm.nih.gov/pubmed/16441078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np050398i
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