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Loss of BH3-only Protein Bim Inhibits Apoptosis of Hemopoietic Cells in the Fetal Liver and Male Germ Cells but Not Neuronal Cells in Bcl-x–deficient Mice

Members of the Bcl-2 family include pro- and antiapoptotic proteins that regulate programmed cell death of developing tissues and death in response to cellular damage. In developing mice, the antiapoptotic Bcl-x(L) is necessary for survival of neural and hematopoietic cells, and consequently, bcl-x–...

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Autori principali: Akhtar, Rizwan S., Klocke, Barbara J., Strasser, Andreas, Roth, Kevin A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Histochemical Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544614/
https://ncbi.nlm.nih.gov/pubmed/18606610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/jhc.2008.951749
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