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Peripheral Aβ subspecies as risk biomarkers of Alzheimer's disease

Plasma Aβ42 and Aβ40 levels are putative biomarkers for Alzheimer's disease (AD), but their significance and predictive value have been inconclusive. In AD transgenic models, plasma and cerebrospinal fluid levels of Aβ42 and Aβ40 increase with age but subsequently decrease when Aβ begins to acc...

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Autores principales: Schupf, Nicole, Tang, Ming X., Fukuyama, Hide, Manly, Jennifer, Andrews, Howard, Mehta, Pankaj, Ravetch, Jeffery, Mayeux, Richard
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544577/
https://ncbi.nlm.nih.gov/pubmed/18779561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805902105
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