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Peripheral Aβ subspecies as risk biomarkers of Alzheimer's disease

Plasma Aβ42 and Aβ40 levels are putative biomarkers for Alzheimer's disease (AD), but their significance and predictive value have been inconclusive. In AD transgenic models, plasma and cerebrospinal fluid levels of Aβ42 and Aβ40 increase with age but subsequently decrease when Aβ begins to acc...

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Detalhes bibliográficos
Main Authors: Schupf, Nicole, Tang, Ming X., Fukuyama, Hide, Manly, Jennifer, Andrews, Howard, Mehta, Pankaj, Ravetch, Jeffery, Mayeux, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544577/
https://ncbi.nlm.nih.gov/pubmed/18779561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805902105
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