FOXO3A genotype is strongly associated with human longevity

Human longevity is a complex phenotype with a significant familial component, yet little is known about its genetic antecedents. Increasing evidence from animal models suggests that the insulin/IGF-1 signaling (IIS) pathway is an important, evolutionarily conserved biological pathway that influences...

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Main Authors: Willcox, Bradley J., Donlon, Timothy A., He, Qimei, Chen, Randi, Grove, John S., Yano, Katsuhiko, Masaki, Kamal H., Willcox, D. Craig, Rodriguez, Beatriz, Curb, J. David
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2008
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544566/
https://ncbi.nlm.nih.gov/pubmed/18765803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801030105
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