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Crystal structure of the β-finger domain of Prp8 reveals analogy to ribosomal proteins
Prp8 stands out among hundreds of splicing factors as a key regulator of spliceosome activation and a potential cofactor of the splicing reaction. We present here the crystal structure of a 274-residue domain (residues 1,822–2,095) near the C terminus of Saccharomyces cerevisiae Prp8. The most strik...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2544537/ https://ncbi.nlm.nih.gov/pubmed/18779563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805960105 |
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