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Isolation of vaccinia virus mutants capable of replicating independently of the host cell nucleus.

alpha-Amanitin-resistant vaccinia virus mutants were isolated after serial viral passages in BSC-40 cells that were carried out in the presence of inhibitory levels (6 micrograms/ml) of alpha-amanitin. One such mutant, alpha-27, was highly refractory (greater than 95%) to alpha-amanitin-mediated inh...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Villarreal, E C, Roseman, N A, Hruby, D E
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1984
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254446/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6748162/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.51.2.359-366.1984
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