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Isolation of vaccinia virus mutants capable of replicating independently of the host cell nucleus.

alpha-Amanitin-resistant vaccinia virus mutants were isolated after serial viral passages in BSC-40 cells that were carried out in the presence of inhibitory levels (6 micrograms/ml) of alpha-amanitin. One such mutant, alpha-27, was highly refractory (greater than 95%) to alpha-amanitin-mediated inh...

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Autors principals: Villarreal, E C, Roseman, N A, Hruby, D E
Format: Artigo
Idioma:Inglês
Publicat: 1984
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC254446/
https://ncbi.nlm.nih.gov/pubmed/6748162
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