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Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutants.

We constructed insertion and deletion mutants with mutations within the adeno-associated virus (AAV) sequences of the infectious recombinant plasmid pSM620. Studies of these mutants revealed at least three AAV phenotypes. Mutants with mutations between 11 and 42 map units were partially or completel...

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Detalhes bibliográficos
Main Authors: Hermonat, P L, Labow, M A, Wright, R, Berns, K I, Muzyczka, N
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC254442/
https://ncbi.nlm.nih.gov/pubmed/6086948
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