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Nuclear Import of Sterol Regulatory Element–binding Protein-2, a Basic Helix-Loop-Helix–Leucine Zipper (bHLH-Zip)–containing Transcription Factor, Occurs through the Direct Interaction of Importin β with HLH-Zip

The sterol regulatory element–binding protein-2 (SREBP-2) is produced as a large precursor molecule attached to the endoplasmic reticulum membrane. In response to the sterol depletion, the N-terminal segment of the precursor, which contains a basic helix-loop-helix–leucine zipper domain, is released...

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Bibliografske podrobnosti
Main Authors: Nagoshi, Emi, Imamoto, Naoko, Sato, Ryuichiro, Yoneda, Yoshihiro
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 1999
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC25438/
https://ncbi.nlm.nih.gov/pubmed/10397761
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