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BiP and Immunoglobulin Light Chain Cooperate to Control the Folding of Heavy Chain and Ensure the Fidelity of Immunoglobulin Assembly

The immunoglobulin (Ig) molecule is composed of two identical heavy chains and two identical light chains (H(2)L(2)). Transport of this heteromeric complex is dependent on the correct assembly of the component parts, which is controlled, in part, by the association of incompletely assembled Ig heavy...

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Hlavní autoři: Lee, Young-Kwang, Brewer, Joseph W., Hellman, Rachel, Hendershot, Linda M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC25436/
https://ncbi.nlm.nih.gov/pubmed/10397760
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