Detection of a Point Mutation Associated with High-Level Isoniazid Resistance in Mycobacterium tuberculosis by Using Real-Time PCR Technology with 3′-Minor Groove Binder-DNA Probes

Tuberculosis remains one of the leading infectious causes of death worldwide. The emergence of drug-resistant strains of Mycobacterium tuberculosis is a serious public health threat. Resistance to isoniazid (INH) is the most prevalent form of resistance in M. tuberculosis and is mainly caused by mut...

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Bibliografiska uppgifter
Huvudupphovsmän: van Doorn, H. Rogier, Claas, Eric C. J., Templeton, Kate E., van der Zanden, Adri G. M., te Koppele Vije, Arianne, de Jong, Menno D., Dankert, Jacob, Kuijper, Ed J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2003
Ämnen:
Mycobacteriology and Aerobic Actinomycetes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC254323/
https://ncbi.nlm.nih.gov/pubmed/14532194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.41.10.4630-4635.2003
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