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Actions of Two Main Metabolites of Propiverine (M-1 and M-2) on Voltage-Dependent L-Type Ca(2+) Currents and Ca(2+) Transients in Murine Urinary Bladder Myocytes
The anticholinergic propiverine, used for the treatment of overactive bladder (OAB) syndrome, has functionally active metabolites (M-1 and M-2), but the site of actions of these metabolites is uncertain. Propiverine is rapidly absorbed after oral administration and is extensively biotransformed in t...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2543115/ https://ncbi.nlm.nih.gov/pubmed/17928569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.130021 |
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