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Prevention of Hepatic Fibrosis in a Murine Model of Metabolic Syndrome with Nonalcoholic Steatohepatitis

The endocannabinoid pathway plays an important role in the regulation of appetite and body weight, hepatic lipid metabolism, and fibrosis. Blockade of the endocannabinoid receptor CB1 with SR141716 promotes weight loss, reduces hepatocyte fatty acid synthesis, and is antifibrotic. D-4F, an apolipopr...

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Bibliografski detalji
Glavni autori: DeLeve, Laurie D., Wang, Xiangdong, Kanel, Gary C., Atkinson, Roscoe D., McCuskey, Robert S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2543068/
https://ncbi.nlm.nih.gov/pubmed/18772330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070720
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