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Incomplete differentiation of engrafted bone marrow endothelial progenitor cells initiates hepatic fibrosis in the rat

Normal liver sinusoidal endothelial cells (LSECs) promote quiescence of hepatic stellate cells. Prior to fibrosis LSECs undergo capillarization, which is permissive for hepatic stellate cell activation, the proximate event in hepatic fibrosis. The aims of this study were to elucidate the nature of a...

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Détails bibliographiques
Publié dans:Hepatology
Auteurs principaux: Maretti-Mira, Ana C., Wang, Xiangdong, Wang, Lei, DeLeve, Laurie D.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387651/
https://ncbi.nlm.nih.gov/pubmed/30141211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30227
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