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Structures of RabGGTase–substrate/product complexes provide insights into the evolution of protein prenylation

Post-translational isoprenylation of proteins is carried out by three related enzymes: farnesyltransferase, geranylgeranyl transferase-I, and Rab geranylgeranyl transferase (RabGGTase). Despite the fact that the last one is responsible for the largest number of individual protein prenylation events...

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Hlavní autoři: Guo, Zhong, Wu, Yao-Wen, Das, Debapratim, Delon, Christine, Cramer, Janinna, Yu, Shen, Thuns, Sandra, Lupilova, Nataliya, Waldmann, Herbert, Brunsveld, Luc, Goody, Roger S, Alexandrov, Kirill, Blankenfeldt, Wulf
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2543052/
https://ncbi.nlm.nih.gov/pubmed/18756270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.164
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