Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression

BACKGROUND: The transcription factor NF-kappaB is a very interesting target molecule for the design on anti-tumor, anti-inflammatory and pro-apoptotic drugs. However, the application of the widely-used molecular docking computational method for the virtual screening of chemical libraries on NF-kappa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Piccagli, Laura, Fabbri, Enrica, Borgatti, Monica, Bezzerri, Valentino, Mancini, Irene, Nicolis, Elena, Dechecchi, Maria C, Lampronti, Ilaria, Cabrini, Giulio, Gambari, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2543017/
https://ncbi.nlm.nih.gov/pubmed/18768082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-8-38
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados