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The catalytic mechanism of Escherichia coli endonuclease VIII: Roles of the intercalation loop and the zinc finger

Endonuclease VIII (Nei) excises oxidatively damaged pyrimidines from DNA and shares structural and functional homology with formamidopyrimidine-DNA glycosylase. Although the structure of Escherichia coli Nei is solved, the functions of many of its amino acid residues involved in catalysis and substr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kropachev, Konstantin Y., Zharkov, Dmitry O., Grollman, Arthur P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542946/
https://ncbi.nlm.nih.gov/pubmed/17002303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060663e
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