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Liver X receptor β (LXRβ): A link between β-sitosterol and amyotrophic lateral sclerosis–Parkinson's dementia
Administration of β-sitosterol (42 mg/kg per day) for 3 weeks to 8-month-old male LXRβ(−/−) mice resulted in the death of motor neurons in the lumbar region of the spinal cord and loss of tyrosine hydroxylase-positive dopaminergic neurons in the substantia nigra. In mice at 5 months of age, β-sitost...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2542868/ https://ncbi.nlm.nih.gov/pubmed/18238900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711599105 |
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