GSK-3β in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1–dependent mechanism

Glycogen synthase kinase–3 (GSK-3) is a widely expressed and highly conserved serine/threonine protein kinase encoded by 2 genes, GSK3A and GSK3B. GSK-3 is thought to be involved in tissue repair and fibrogenesis, but its role in these processes is currently unknown. To investigate the function of G...

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Autori principali: Kapoor, Mohit, Liu, Shangxi, Shi-wen, Xu, Huh, Kun, McCann, Matthew, Denton, Christopher P., Woodgett, James R., Abraham, David J., Leask, Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542848/
https://ncbi.nlm.nih.gov/pubmed/18802478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35381
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