Contrasting Use of CCR5 Structural Determinants by R5 and R5X4 Variants within a Human Immunodeficiency Virus Type 1 Primary Isolate Quasispecies

Macrophagetropic R5 human immunodeficiency virus type 1 (HIV-1) isolates often evolve into dualtropic R5X4 variants during disease progression. The structural basis for CCR5 coreceptor function has been studied in a limited number of prototype strains and suggests that R5 and R5X4 Envs interact diff...

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Detalhes bibliográficos
Main Authors: Yi, Yanjie, Singh, Anjali, Shaheen, Farida, Louden, Andrew, Lee, ChuHee, Collman, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC254272/
https://ncbi.nlm.nih.gov/pubmed/14581542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.22.12057-12066.2003
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