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De Novo Design of a Single Chain Diphenylporphyrin Metalloprotein
We describe the computational design of a single-chain four-helix bundle that noncovalently self-assembles with fully synthetic non-natural porphyrin cofactors. With this strategy, both the electronic structure of the cofactor as well as its protein environment may be varied to explore and modulate...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2542652/ https://ncbi.nlm.nih.gov/pubmed/17691729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja071199j |
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