Gamma Interferon Is Critical for Neuronal Viral Clearance and Protection in a Susceptible Mouse Strain following Early Intracranial Theiler's Murine Encephalomyelitis Virus Infection

We evaluated the role of gamma interferon (IFN-γ) in protecting neurons from virus-induced injury following central nervous system infection. IFN-γ(−/−) and IFN-γ(+/+) mice of the resistant major histocompatibility complex (MHC) H-2(b) haplotype and intracerebrally infected with Theiler's murine enc...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Rodriguez, Moses, Zoecklein, Laurie J., Howe, Charles L., Pavelko, Kevin D., Gamez, Jeff D., Nakane, Shunya, Papke, Louisa M.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2003
Fag:	Pathogenesis and Immunity
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254254/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14581562/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.22.12252-12265.2003
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