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Telomere Repeat Binding Factors TRF1, TRF2, and hRAP1 Modulate Replication of Epstein-Barr Virus OriP

Epstein-Barr virus OriP confers cell cycle-dependent DNA replication and stable maintenance on plasmids in EBNA1-positive cells. The dyad symmetry region of OriP contains four EBNA1 binding sites that are punctuated by 9-bp repeats referred to as nonamers. Previous work has shown that the nonamers b...

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Bibliografiske detaljer
Main Authors: Deng, Zhong, Atanasiu, Constandache, Burg, John S., Broccoli, Dominique, Lieberman, Paul M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC254251/
https://ncbi.nlm.nih.gov/pubmed/14581536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.22.11992-12001.2003
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