Ero1L, a thiol oxidase, is required for Notch signaling through cysteine bridge formation of the Lin12-Notch repeats in Drosophila melanogaster

Notch-mediated cell–cell communication regulates numerous developmental processes and cell fate decisions. Through a mosaic genetic screen in Drosophila melanogaster, we identified a role in Notch signaling for a conserved thiol oxidase, endoplasmic reticulum (ER) oxidoreductin 1–like (Ero1L). Altho...

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Autors principals: Tien, An-Chi, Rajan, Akhila, Schulze, Karen L., Ryoo, Hyung Don, Acar, Melih, Steller, Hermann, Bellen, Hugo J.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2008
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542473/
https://ncbi.nlm.nih.gov/pubmed/18809725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805001
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