Type I interferon-dependent gene MxA in perinatal HIV-infected patients under antiretroviral therapy as marker for therapy failure and blood plasmacytoid dendritic cells depletion

BACKGROUND: To determine the role of interferon-alpha in controlling HIV infection we phenotypically and functionally analyzed circulating plasmacytoid dendritic cells (pDC), which are known to be the highest interferon-alpha producing cells, in 33 perinatally infected HIV(+ )patients undergoing sta...

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Détails bibliographiques
Auteurs principaux: Badolato, Raffaele, Ghidini, Claudia, Facchetti, Fabio, Serana, Federico, Sottini, Alessandra, Chiarini, Marco, Spinelli, Elena, Lonardi, Silvia, Plebani, Alessandro, Caimi, Luigi, Imberti, Luisa
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2008
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542353/
https://ncbi.nlm.nih.gov/pubmed/18782441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-6-49
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