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Genetic and biological analyses of a herpes simplex virus intertypic recombinant reduced specifically for neurovirulence.

RS6 is a herpes simplex virus intertypic recombinant derived from type 1 strain 17 syn+ and type 2 strain HG52. With a 50% lethal dose of about 10(5) PFU after intracerebral inoculation of mice, RS6 was approximately 100,000 times less neurovirulent than either of its wild-type parental viruses were...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Javier, R T, Thompson, R L, Stevens, J G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1987
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC254206/
https://ncbi.nlm.nih.gov/pubmed/3033324
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