Inhibition of the tyrosine kinase activity of v-src, v-fgr, and v-yes gene products by a monoclonal antibody which binds both amino and carboxy peptide fragments of pp60v-src.
A monoclonal antibody, R2D2, raised to the src gene product of Rous sarcoma virus was found to inhibit the tyrosine protein kinase activity of pp60v-src in autophosphorylation reactions and in reactions involving exogenously added substrates, such as casein and histone. R2D2 also inhibited the enzym...
Guardado en:
| Publicado en: | J Virol |
|---|---|
| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1987
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254200/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2437325/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.6.1927-1937.1987 |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|