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High-frequency homologous recombination in vaccinia virus DNA.

A recombinant vaccinia virus genome was constructed in which the viral thymidine kinase (tk) gene was placed between direct repeats of a 1.5-kilobase-pair DNA sequence of heterologous origin. When forced to replicate in tk- cells in the presence of methotrexate (i.e., under tk+-selective conditions)...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
1. Verfasser: Ball, L A
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1987
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254181/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3573150/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.6.1788-1795.1987
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